Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NEK2 | P51955 | 2/20 | 1.00 |
| ▸ | CDK1 | P06493 | 1/20 | 1.00 |
| ▸ | CCNB1 | P14635 | 1/20 | 1.00 |
| ▸ | TLK2 | Q86UE8 | 6/20 | 0.76 |
| ▸ | PDPK1 | O15530 | 6/20 | 0.74 |
| ▸ | JAK3 | P52333 | 4/20 | 0.74 |
| ▸ | PAK4 | O96013 | 2/20 | 0.70 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.66 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.65 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.65 |
| ▸ | FLT1 | P17948 | 1/20 | 0.65 |
| ▸ | KDR | P35968 | 1/20 | 0.65 |
| ▸ | RET | P07949 | 2/20 | 0.61 |
| ▸ | FLT3 | P36888 | 1/20 | 0.61 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12200908 | 1.00 | NEK2 (1.00) | NEK2CDK1CCNB1TLK2PDPK1 | |
| SCHEMBL20945 | 0.85 | TLK2 (1.00) | NEK2CDK1CCNB1TLK2PDPK1 | |
| SCHEMBL20944 | 0.85 | TLK2 (1.00) | NEK2CDK1CCNB1TLK2PDPK1 | |
| SCHEMBL5728434 | 0.84 | PDPK1 (1.00) | NEK2CDK1CCNB1TLK2PDPK1 | |
| SCHEMBL13080513 | 0.84 | TLK2 (1.00) | NEK2CDK1CCNB1TLK2PDPK1 | |
| SCHEMBL5728440 | 0.84 | PDPK1 (1.00) | NEK2CDK1CCNB1TLK2PDPK1 | |
| SCHEMBL5361523 | 0.81 | PDPK1 (1.00) | NEK2CDK1CCNB1TLK2PDPK1 | |
| SCHEMBL5728671 | 0.81 | PDPK1 (1.00) | NEK2CDK1CCNB1TLK2PDPK1 | |
| SCHEMBL5366002 | 0.81 | PDPK1 (0.80) | NEK2CDK1CCNB1TLK2PDPK1 | |
| SCHEMBL5374151 | 0.81 | PDPK1 (0.78) | NEK2CDK1CCNB1TLK2PDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4662319-A2 | PERSONALIZED CRISPR PROFILING FOR CANCER | Integrate Bioscience LLC (US) | 2025-12-17 | — | — | EP | disclosed |
| WO-2024168301-A2 | PERSONALIZED CRISPR PROFILING FOR CANCER | FUNCTION ONCOLOGY, INC. (US) | 2024-08-15 | — | — | WO | disclosed |