SCHEMBL31061499

SCHEMBL31061499

CN(C(=O)Cn1c(=O)n(C)c2ccc(-c3ccccc3)cc21)c1ccccc1

nearest known ligand 0.64

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ TSPO P30536 1/20 0.54
▸ GRM2 Q14416 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5425119 0.87 TSPO (0.53) TSPO
SCHEMBL5417355 0.85 TSPO (0.50) TSPO
SCHEMBL5422139 0.85 TSPO (0.52) TSPO
SCHEMBL5416189 0.78 TSPO (0.53) TSPO
SCHEMBL15256809 0.77 TSPO (0.52) TSPOGRM2
SCHEMBL15258355 0.75 POLB (0.61) GRM2
SCHEMBL7215601 0.74 TSPO (0.58) TSPO
SCHEMBL14992557 0.73 GRM2 (0.89) GRM2
SCHEMBL5422142 0.73 POLQ (0.45) TSPO
SCHEMBL5434013 0.71 TSPO (0.49) TSPO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4662319-A2 PERSONALIZED CRISPR PROFILING FOR CANCER Integrate Bioscience LLC (US) 2025-12-17 — — EP disclosed
WO-2024168301-A2 PERSONALIZED CRISPR PROFILING FOR CANCER FUNCTION ONCOLOGY, INC. (US) 2024-08-15 — — WO disclosed
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