SCHEMBL31063102

SCHEMBL31063102

CCOC(=O)Cc1cc(Cl)ccc1OCC1CC1

nearest known ligand 0.52

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PTGER1 P34995 7/20 0.52
GAA P10253 1/20 0.42
HTR2C P28335 2/20 0.42
HTR2B P41595 2/20 0.42
MEN1 O00255 1/20 0.42
ALDH1A1 P00352 1/20 0.42
KMT2A Q03164 1/20 0.42
RBP4 P02753 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.40
TSHR P16473 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28942782 0.80 LMNA (0.48) GAAMEN1ALDH1A1KMT2ASMN1; SMN2
SCHEMBL20612921 0.78 FFAR4 (0.44) ALDH1A1
SCHEMBL19899240 0.78 GAA (0.43) GAAMEN1ALDH1A1KMT2ASMN1; SMN2
SCHEMBL14098668 0.78 PTGER1 (0.57) PTGER1
SCHEMBL16731569 0.76 KMT2A (0.49) GAAMEN1ALDH1A1KMT2ASMN1; SMN2
SCHEMBL2958946 0.76 PTGER1 (0.76) PTGER1
SCHEMBL31063330 0.76 PTGER1 (0.43) PTGER1GAAHTR2CHTR2BMEN1
SCHEMBL4091719 0.75 PTGER1 (0.56) PTGER1
SCHEMBL838576 0.75 KMT2A (0.48) GAAMEN1ALDH1A1KMT2ASMN1; SMN2
SCHEMBL137173 0.75 ABL1 (0.43) GAAALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4665339-A1 INHIBITING ALPHA V BETA 8 INTEGRIN Morphic Therapeutic, Inc. (US) 2025-12-24 EP disclosed
WO-2024173570-A1 INHIBITING αvβ8 INTEGRIN MORPHIC THERAPEUTIC, INC. (US) 2024-08-22 WO disclosed