Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAV | P06756 | 5/20 | 0.37 |
| ▸ | ITGB6 | P18564 | 5/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.35 |
| ▸ | PIK3R1 | P27986 | 4/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.34 |
| ▸ | MPO | P05164 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 2/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.32 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31582686 | 0.89 | ITGAV (0.43) | ITGAVITGB6GPR119MPONPC1 | |
| SCHEMBL20141376 | 0.85 | ITGAV (0.44) | ITGAVITGB6GPR119MPONPC1 | |
| SCHEMBL31063024 | 0.85 | ITGAV (0.47) | ITGAVITGB6GPR119PIK3CDNPC1 | |
| SCHEMBL31062885 | 0.85 | ITGAV (0.47) | ITGAVITGB6GPR119PIK3CDNPC1 | |
| SCHEMBL31063505 | 0.84 | ITGAV (0.54) | ITGAVITGB6 | |
| SCHEMBL28744015 | 0.80 | ITGAV (0.44) | ITGAVITGB6GPR119NPC1RAB9A | |
| SCHEMBL20481168 | 0.80 | MPO (0.38) | ITGAVITGB6GPR119MPONPC1 | |
| SCHEMBL21328581 | 0.79 | MPO (0.39) | ITGAVITGB6GPR119MPONPC1 | |
| SCHEMBL1840941 | 0.79 | MPO (0.39) | ITGAVITGB6GPR119MPONPC1 | |
| SCHEMBL16607380 | 0.79 | ITGAV (0.40) | ITGAVITGB6GPR119MPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4665339-A1 | INHIBITING ALPHA V BETA 8 INTEGRIN | Morphic Therapeutic, Inc. (US) | 2025-12-24 | — | — | EP | disclosed |
| WO-2024173570-A1 | INHIBITING αvβ8 INTEGRIN | MORPHIC THERAPEUTIC, INC. (US) | 2024-08-22 | — | — | WO | disclosed |