Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.46 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.41 |
| ▸ | GRM1 | Q13255 | 9/20 | 0.41 |
| ▸ | GRM5 | P41594 | 8/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | WNT3A | P56704 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | JAK1 | P23458 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24319593 | 0.86 | TLR7 (0.52) | TLR7PDK4GRM1GRM5NAMPT | |
| SCHEMBL14710349 | 0.78 | NAMPT (0.53) | PDK4GRM1GRM5NAMPTWNT3A | |
| SCHEMBL904163 | 0.77 | GRM1 (0.52) | TLR7PDK4GRM1GRM5NAMPT | |
| SCHEMBL31342062 | 0.77 | PDK4 (0.50) | PDK4GRM1GRM5NAMPTWNT3A | |
| SCHEMBL31063104 | 0.77 | DPP4 (0.48) | TLR7PDE4BGPR119 | |
| SCHEMBL28672677 | 0.75 | GRM1 (0.56) | TLR7PDK4GRM1GRM5NAMPT | |
| SCHEMBL19701844 | 0.75 | GRM1 (0.54) | TLR7PDK4GRM1GRM5NAMPT | |
| SCHEMBL19701839 | 0.75 | GRM1 (0.50) | TLR7PDK4GRM1GRM5NAMPT | |
| SCHEMBL979984 | 0.74 | GRM1 (0.54) | TLR7PDK4GRM1GRM5NAMPT | |
| SCHEMBL15178435 | 0.74 | NAMPT (0.54) | TLR7PDK4GRM1GRM5NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4665339-A1 | INHIBITING ALPHA V BETA 8 INTEGRIN | Morphic Therapeutic, Inc. (US) | 2025-12-24 | — | — | EP | disclosed |
| WO-2024173570-A1 | INHIBITING αvβ8 INTEGRIN | MORPHIC THERAPEUTIC, INC. (US) | 2024-08-22 | — | — | WO | disclosed |