Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 4/20 | 0.45 |
| ▸ | WDR77 | Q9BQA1 | 4/20 | 0.45 |
| ▸ | ITGAV | P06756 | 2/20 | 0.42 |
| ▸ | ITGB6 | P18564 | 2/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | IDH1 | O75874 | 2/20 | 0.38 |
| ▸ | FNTA | P49354 | 1/20 | 0.37 |
| ▸ | FNTB | P49356 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31063278 | 1.00 | PRMT5 (0.45) | PRMT5WDR77ITGAVITGB6GPR119 | |
| SCHEMBL31063316 | 1.00 | PRMT5 (0.45) | PRMT5WDR77ITGAVITGB6GPR119 | |
| SCHEMBL31063019 | 1.00 | PRMT5 (0.45) | PRMT5WDR77ITGAVITGB6GPR119 | |
| SCHEMBL31063205 | 1.00 | PRMT5 (0.45) | PRMT5WDR77ITGAVITGB6GPR119 | |
| SCHEMBL31063168 | 0.99 | PRMT5 (0.46) | PRMT5WDR77ITGAVITGB6GPR119 | |
| SCHEMBL31063128 | 0.99 | PRMT5 (0.46) | PRMT5WDR77ITGAVITGB6GPR119 | |
| SCHEMBL31063069 | 0.99 | PRMT5 (0.46) | PRMT5WDR77ITGAVITGB6GPR119 | |
| SCHEMBL31582705 | 0.94 | PRMT5 (0.41) | PRMT5WDR77ITGAVITGB6GPR119 | |
| SCHEMBL20140705 | 0.91 | PRMT5 (0.42) | PRMT5WDR77ITGAVITGB6GPR119 | |
| SCHEMBL21767423 | 0.85 | GPR119 (0.40) | PRMT5WDR77ITGAVITGB6GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4665339-A1 | INHIBITING ALPHA V BETA 8 INTEGRIN | Morphic Therapeutic, Inc. (US) | 2025-12-24 | — | — | EP | disclosed |
| WO-2024173570-A1 | INHIBITING αvβ8 INTEGRIN | MORPHIC THERAPEUTIC, INC. (US) | 2024-08-22 | — | — | WO | disclosed |