Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | DPP4 | P27487 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3800298 | 0.88 | HSD17B10 (0.67) | HSD17B10MEN1KMT2AALDH1A1DPP4 | |
| SCHEMBL30104116 | 0.88 | HSD17B10 (0.67) | HSD17B10MEN1KMT2AALDH1A1DPP4 | |
| SCHEMBL8282635 | 0.82 | CYP3A4 (0.51) | HSD17B10MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL23616869 | 0.81 | MAPK8 (0.48) | HSD17B10MEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL21455827 | 0.81 | ALDH1A1 (0.48) | MEN1KMT2AALDH1A1MAPTMAPK1 | |
| SCHEMBL31063033 | 0.80 | DPP4 (0.41) | HSD17B10ALDH1A1DPP4TSHR | |
| SCHEMBL6343901 | 0.80 | DPP4 (0.47) | HSD17B10MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL31063213 | 0.78 | DPP4 (0.46) | HSD17B10MEN1KMT2AALDH1A1DPP4 | |
| SCHEMBL2190989 | 0.78 | DPP4 (0.49) | HSD17B10MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL31053274 | 0.78 | KDM4E (0.50) | HSD17B10MEN1KMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4665339-A1 | INHIBITING ALPHA V BETA 8 INTEGRIN | Morphic Therapeutic, Inc. (US) | 2025-12-24 | — | — | EP | disclosed |
| WO-2024173570-A1 | INHIBITING αvβ8 INTEGRIN | MORPHIC THERAPEUTIC, INC. (US) | 2024-08-22 | — | — | WO | disclosed |