Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.42 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.42 |
| ▸ | FLT3 | P36888 | 1/20 | 0.42 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.42 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.42 |
| ▸ | CDK1 | P06493 | 1/20 | 0.42 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.42 |
| ▸ | GSK3A | P49840 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TNIK | Q9UKE5 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23407789 | 0.95 | APP (0.44) | APPIDO1RAB9AMAPTNPC1 | |
| SCHEMBL30203744 | 0.95 | APP (0.44) | APPIDO1RAB9AMAPTNPC1 | |
| SCHEMBL30203661 | 0.81 | IDO1 (0.42) | IDO1RAB9AMAPTNPC1MAPK1 | |
| SCHEMBL23407782 | 0.81 | IDO1 (0.42) | IDO1RAB9AMAPTNPC1MAPK1 | |
| SCHEMBL30203597 | 0.80 | IDO1 (0.43) | IDO1RAB9AMAPTNPC1MAPK1 | |
| SCHEMBL26094088 | 0.80 | RAB9A (0.56) | APPIDO1RAB9AMAPTNPC1 | |
| SCHEMBL23407808 | 0.78 | APP (0.44) | APPIDO1RAB9AMAPTNPC1 | |
| SCHEMBL30203619 | 0.78 | APP (0.44) | APPIDO1RAB9AMAPTNPC1 | |
| SCHEMBL30203530 | 0.78 | APP (0.44) | APPIDO1RAB9AMAPTNPC1 | |
| SCHEMBL23407774 | 0.76 | IDO1 (0.44) | IDO1RAB9AMAPTNPC1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024200263-A1 | 2-STYRYLBENZOTHIAZOLE DERIVATIVES AS α-SYNUCLEIN BINDING COMPOUNDS | EBERHARD KARLS UNIVERSITAET TUEBINGEN MEDIZINISCHE FAKULTAET (DE) | 2024-10-03 | — | — | WO | disclosed |
| EP-4438597-A1 | 2-STYRYLBENZOTHIAZOLE DERIVATIVES AS A-SYNUCLEIN BINDING COMPOUNDS | Eberhard Karls Universität Tübingen Medizinische Fakultät (DE) | 2024-10-02 | — | — | EP | disclosed |