Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | ATP4A | P20648 | 4/20 | 0.53 |
| ▸ | ATP4B | P51164 | 4/20 | 0.53 |
| ▸ | SNCA | P37840 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | APP | P05067 | 1/20 | 0.48 |
| ▸ | INSR | P06213 | 1/20 | 0.48 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31063734 | 0.92 | ATP4A (0.60) | RAB9ANPC1ALDH1A1KDM4EPOLB | |
| SCHEMBL31063740 | 0.91 | ATP4A (0.58) | RAB9ANPC1ALDH1A1KDM4EPOLB | |
| SCHEMBL31063864 | 0.83 | NPC1 (0.55) | RAB9ANPC1ALDH1A1ATP4AATP4B | |
| SCHEMBL31063751 | 0.82 | NPC1 (0.54) | RAB9ANPC1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL31063719 | 0.81 | MEN1 (0.55) | RAB9ANPC1ALDH1A1KDM4EPOLB | |
| SCHEMBL31063618 | 0.81 | SMN1; SMN2 (0.57) | RAB9ANPC1ALDH1A1KDM4EATP4A | |
| SCHEMBL26467451 | 0.79 | MAPT (0.57) | RAB9ANPC1ALDH1A1KDM4EPOLB | |
| SCHEMBL11776645 | 0.79 | MAPT (0.57) | RAB9ANPC1ALDH1A1KDM4EPOLB | |
| SCHEMBL31063724 | 0.79 | MAPT (0.53) | RAB9ANPC1ALDH1A1KDM4EPOLB | |
| SCHEMBL21889377 | 0.77 | MEN1 (0.56) | RAB9ANPC1ALDH1A1KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024200263-A1 | 2-STYRYLBENZOTHIAZOLE DERIVATIVES AS α-SYNUCLEIN BINDING COMPOUNDS | EBERHARD KARLS UNIVERSITAET TUEBINGEN MEDIZINISCHE FAKULTAET (DE) | 2024-10-03 | — | — | WO | disclosed |
| EP-4438597-A1 | 2-STYRYLBENZOTHIAZOLE DERIVATIVES AS A-SYNUCLEIN BINDING COMPOUNDS | Eberhard Karls Universität Tübingen Medizinische Fakultät (DE) | 2024-10-02 | — | — | EP | disclosed |