⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11703769 | 0.87 | ALDH1A1 (0.32) | — | |
| SCHEMBL585309 | 0.87 | — | — | |
| SCHEMBL10902293 | 0.85 | — | — | |
| SCHEMBL3543914 | 0.85 | — | — | |
| SCHEMBL11820745 | 0.85 | — | — | |
| SCHEMBL1019544 | 0.83 | — | — | |
| SCHEMBL2389136 | 0.83 | — | — | |
| SCHEMBL5161804 | 0.83 | — | — | |
| SCHEMBL11834594 | 0.81 | — | — | |
| SCHEMBL8990343 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 828 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080119497-A1 | Hydroxyalkyl substituted pyrido-7-pyrimidin-7-ones | ROCHE PALO ALTO LLC | 2008-05-22 | — | — | US | claimed |
| US-7348331-B2 | Hydroxyalkyl substituted pyrido-7-pyrimidin-7-ones | ROCHE PALO ALTO LLC (US) | 2008-03-25 | — | — | US | claimed |
| EP-1539755-B1 | 6-ALKOXY-PYRIDO-PYRIMIDINES AS P-38 MAP KINASE INHIBITORS | HOFFMANN LA ROCHE (CH) | 2007-09-26 | — | — | EP | claimed |
| EP-1539755-A1 | 6-ALKOXY-PYRIDO-PYRIMIDINES AS P-38 MAP KINASE INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2005-06-15 | — | — | EP | claimed |
| US-20050107408-A1 | Hydroxyalkyl substituted pyrido-7-pyrimidin-7-ones | ROCHE PALO ALTO LLC | 2005-05-19 | — | — | US | claimed |
| US-20040038999-A1 | 6-alkoxy-pyrido-pyrimidines | ROCHE PALO ALTO LLC | 2004-02-26 | — | — | US | claimed |
| WO-2004014907-A1 | 6-ALKOXY-PYRIDO-PYRIMIDINES AS P-38 MAP KINASE INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2004-02-19 | — | — | WO | claimed |
| US-20030003396-A1 | Optical data carrier comprising a merocyanine dye as light-absorbent compound in the information layer | LANXESS DEUTSCHLAND GMBH (DE) | 2003-01-02 | — | — | US | claimed |
| EP-3601294-B1 | ATF3 INDUCTION COMPOUNDS | UNIV TAIPEI MEDICAL (TW) | 2024-07-10 | — | — | EP | disclosed |
| WO-2024141444-A1 | NEW BENZIMIDAZOLE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2024-07-04 | — | — | WO | disclosed |
| US-20240158356-A1 | DIAMINOPYRIMIDINES AS P2X3 AND P2X2/3 ANTAGONISTS | ROCHE PALO ALTO LLC (US) | 2024-05-16 | — | — | US | disclosed |
| CN-117777229-A | Process for preparing an A Long Meisu ring analog | 豪夫迈·罗氏有限公司 | 2024-03-29 | — | — | CN | disclosed |
| US-20240043661-A1 | CYCLODEXTRIN DIMERS AND USES THEREOF | UNDERDOG PHARMACEUTICALS INC (US) | 2024-02-08 | — | — | US | disclosed |
| CN-110475766-B | Process for preparing an A Long Meisu ring analog | 豪夫迈·罗氏有限公司 | 2023-12-29 | — | — | CN | disclosed |
| US-20040038999-A1 | 6-alkoxy-pyrido-pyrimidines | ROCHE PALO ALTO LLC | 2004-02-26 | — | — | US | disclosed |
| WO-2004014907-A1 | 6-ALKOXY-PYRIDO-PYRIMIDINES AS P-38 MAP KINASE INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2004-02-19 | — | — | WO | disclosed |
| US-5641430-A | Silacyclohexane compounds, preparation thereof, liquid crystal compositions comprising the same, and liquid crystal devices comprising the compositions | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1997-06-24 | — | — | US | disclosed |
| US-4971871-A | ZINC OXIDE AND RESIN BINDER | FUJI PHOTO FILM CO., LTD. (JP) | 1990-11-20 | — | — | US | disclosed |
| US-4335138-A | HYPNOTIC, SEDATIVE | BASF AKTIENGESELLSCHAFT (DE) | 1982-06-15 | — | — | US | disclosed |
| EP-0026369-A2 | Carbamates, their preparation and pharmaceutical compositions containing them | BASF Aktiengesellschaft (DE) | 1981-04-08 | — | — | EP | disclosed |