Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 10/20 | 0.48 |
| ▸ | CDK9 | P50750 | 7/20 | 0.48 |
| ▸ | CDK7 | P50613 | 9/20 | 0.44 |
| ▸ | CDK4 | P11802 | 3/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.35 |
| ▸ | CCNH | P51946 | 6/20 | 0.34 |
| ▸ | MNAT1 | P51948 | 6/20 | 0.34 |
| ▸ | TYK2 | P29597 | 1/20 | 0.33 |
| ▸ | CCR2 | P41597 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31064216 | 0.87 | CDK2 (0.49) | CDK2CDK9CDK7CDK4GSK3B | |
| SCHEMBL31064177 | 0.86 | CDK2 (0.47) | CDK2CDK9CDK7CDK4GSK3B | |
| SCHEMBL31064123 | 0.86 | CDK2 (0.48) | CDK2CDK9CDK7CDK4CCNH | |
| SCHEMBL31064176 | 0.83 | CDK7 (0.48) | CDK2CDK9CDK7CDK4GSK3B | |
| SCHEMBL31064166 | 0.80 | CDK2 (0.49) | CDK2CDK9CDK7CDK4GSK3B | |
| SCHEMBL31064076 | 0.77 | CDK2 (0.53) | CDK2CDK9CDK7CDK4CCNH | |
| SCHEMBL31064222 | 0.77 | CDK2 (0.45) | CDK2CDK9CDK7CDK4GSK3B | |
| SCHEMBL31064119 | 0.77 | CDK2 (0.45) | CDK2CDK9CDK7CDK4GSK3B | |
| SCHEMBL31064063 | 0.76 | CDK2 (0.48) | CDK2CDK9CDK7CDK4GSK3B | |
| SCHEMBL20971697 | 0.74 | CDK4 (0.71) | CDK9CDK7CDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024175024-A1 | NEW FUSED HETEROCYCLIC COMPOUND AS CDKS INHIBITOR AND USE THEREOF | 杭州德睿智药科技有限公司 | 2024-08-29 | — | — | WO | disclosed |