Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 9/20 | 0.49 |
| ▸ | CDK9 | P50750 | 6/20 | 0.49 |
| ▸ | TTK | P33981 | 7/20 | 0.41 |
| ▸ | CDK7 | P50613 | 7/20 | 0.40 |
| ▸ | CDK4 | P11802 | 3/20 | 0.40 |
| ▸ | CCNH | P51946 | 4/20 | 0.37 |
| ▸ | MNAT1 | P51948 | 4/20 | 0.37 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31064063 | 0.82 | CDK2 (0.48) | CDK2CDK9CDK7CDK4CCNH | |
| SCHEMBL31064057 | 0.81 | CDK2 (0.47) | CDK2CDK9CDK7CDK4CCNH | |
| SCHEMBL31064007 | 0.80 | CDK2 (0.48) | CDK2CDK9CDK7CDK4CCNH | |
| SCHEMBL31064147 | 0.78 | CDK7 (0.37) | CDK2CDK9CDK7CDK4CCNH | |
| SCHEMBL31064054 | 0.77 | CDK2 (0.41) | CDK2CDK9CDK7CDK4CCNH | |
| SCHEMBL31064293 | 0.77 | CDK7 (0.47) | CDK2CDK9CDK7CDK4CCNH | |
| SCHEMBL31064022 | 0.74 | CDK7 (0.38) | CDK2CDK9CDK7CDK4CCNH | |
| SCHEMBL31064216 | 0.71 | CDK2 (0.49) | CDK2CDK9CDK7CDK4CCNH | |
| SCHEMBL31064180 | 0.71 | CDK2 (0.43) | CDK2CDK9CDK7CDK4CCNH | |
| SCHEMBL31064177 | 0.69 | CDK2 (0.47) | CDK2CDK9CDK7CDK4CCNH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024175024-A1 | NEW FUSED HETEROCYCLIC COMPOUND AS CDKS INHIBITOR AND USE THEREOF | 杭州德睿智药科技有限公司 | 2024-08-29 | — | — | WO | disclosed |