Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 13/20 | 0.37 |
| ▸ | MTOR | P42345 | 6/20 | 0.37 |
| ▸ | PRKDC | P78527 | 3/20 | 0.37 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.37 |
| ▸ | ATR | Q13535 | 3/20 | 0.37 |
| ▸ | ATRIP | Q8WXE1 | 1/20 | 0.37 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 7/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.32 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PI4KA | P42356 | 1/20 | 0.31 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30192398 | 0.85 | PIK3CB (0.36) | ATMMTORPRKDCPIK3CBATR | |
| SCHEMBL23119186 | 0.84 | ATM (0.49) | ATMMTORPRKDCPIK3CBATR | |
| SCHEMBL23119298 | 0.84 | ATM (0.54) | ATMMTORPRKDCPIK3CBATR | |
| SCHEMBL23093830 | 0.84 | ATM (0.54) | ATMMTORPRKDCPIK3CBATR | |
| SCHEMBL23119299 | 0.84 | ATM (0.54) | ATMMTORPRKDCPIK3CBATR | |
| SCHEMBL29687994 | 0.83 | ATM (0.46) | ATMMTORPRKDCPIK3CBATR | |
| SCHEMBL23093835 | 0.83 | ATM (0.46) | ATMMTORPRKDCPIK3CBATR | |
| SCHEMBL29688245 | 0.82 | ATM (0.45) | ATMMTORPRKDCPIK3CBATR | |
| SCHEMBL28793970 | 0.82 | ATM (0.39) | ATMMTORPRKDCPIK3CBATR | |
| SCHEMBL29742725 | 0.82 | ATM (0.39) | ATMMTORPRKDCPIK3CBATR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119215050-A | Application of substituted imidazoquinoxaline compound in preparation of anti-cancer drugs | 上海瑛派药业有限公司 | 2024-12-31 | — | — | CN | disclosed |
| CN-119080781-A | Substituted imidazoquinoxaline compounds and uses thereof | 上海瑛派药业有限公司 | 2024-12-06 | — | — | CN | disclosed |
| CN-114787162-B | Substituted imidazoquinoxaline compounds and uses thereof | 上海瑛派药业有限公司 | 2024-09-03 | — | — | CN | disclosed |