Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK7 | P50613 | 15/20 | 0.54 |
| ▸ | CDK2 | P24941 | 7/20 | 0.54 |
| ▸ | CDK9 | P50750 | 7/20 | 0.54 |
| ▸ | CDK4 | P11802 | 2/20 | 0.54 |
| ▸ | CCNH | P51946 | 13/20 | 0.48 |
| ▸ | MNAT1 | P51948 | 13/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31064224 | 0.88 | CDK9 (0.42) | CDK7CDK2CDK9CDK4CCNH | |
| SCHEMBL31064009 | 0.87 | CDK9 (0.44) | CDK7CDK2CDK9CDK4 | |
| SCHEMBL31064174 | 0.86 | CDK7 (0.49) | CDK7CDK2CDK9CDK4CCNH | |
| SCHEMBL31064184 | 0.86 | CDK2 (0.51) | CDK7CDK2CDK9CDK4CCNH | |
| SCHEMBL31064011 | 0.85 | CDK2 (0.52) | CDK7CDK2CDK9CDK4CCNH | |
| SCHEMBL31064021 | 0.84 | CDK9 (0.40) | CDK7CDK2CDK9CDK4CCNH | |
| SCHEMBL31064092 | 0.84 | CDK7 (0.57) | CDK7CDK2CDK9CDK4CCNH | |
| SCHEMBL31064087 | 0.83 | CDK7 (0.45) | CDK7CDK2CDK9CDK4CCNH | |
| SCHEMBL31064086 | 0.82 | CDK2 (0.52) | CDK7CDK2CDK9CDK4CCNH | |
| SCHEMBL30865954 | 0.82 | CDK2 (0.56) | CDK7CDK2CDK9CDK4CCNH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024175024-A1 | NEW FUSED HETEROCYCLIC COMPOUND AS CDKS INHIBITOR AND USE THEREOF | 杭州德睿智药科技有限公司 | 2024-08-29 | — | — | WO | disclosed |