Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | PREP | P48147 | 4/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29703403 | 0.83 | HPGD (0.64) | HPGDPREPEPHX1RECQLPIK3CD | |
| SCHEMBL29703410 | 0.83 | HPGD (0.64) | HPGDPREPEPHX1RECQLPIK3CD | |
| SCHEMBL2721275 | 0.83 | HPGD (0.64) | HPGDPREPEPHX1RECQLPIK3CD | |
| SCHEMBL17392565 | 0.80 | HPGD (0.51) | HPGDEPHX1RECQLPIK3CDMEN1 | |
| SCHEMBL6988508 | 0.80 | HPGD (0.51) | HPGDEPHX1RECQLPIK3CDMEN1 | |
| SCHEMBL13219346 | 0.80 | HPGD (0.51) | HPGDEPHX1RECQLPIK3CDMEN1 | |
| SCHEMBL7299784 | 0.80 | HPGD (0.51) | HPGDEPHX1RECQLPIK3CDMEN1 | |
| SCHEMBL65675 | 0.80 | HPGD (0.51) | HPGDEPHX1RECQLPIK3CDMEN1 | |
| SCHEMBL12345350 | 0.79 | CHRM2 (0.68) | HPGDPREPEPHX1CHRM2CHRM1 | |
| SCHEMBL20635190 | 0.79 | CHRM2 (0.68) | HPGDPREPEPHX1CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024175024-A1 | NEW FUSED HETEROCYCLIC COMPOUND AS CDKS INHIBITOR AND USE THEREOF | 杭州德睿智药科技有限公司 | 2024-08-29 | — | — | WO | disclosed |