SCHEMBL31065125

SCHEMBL31065125

Cc1cc(NC(=O)c2ccc([N+](=O)[O-])cc2N2CCC3(CC2)CC3)cc(N2CCC(F)(F)CC2)n1

nearest known ligand 0.66

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ KIF18A Q8NI77 20/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27455433 0.90 KIF18A (0.55) KIF18A
SCHEMBL22122582 0.87 KIF18A (0.71) KIF18A
SCHEMBL29367667 0.87 KIF18A (0.71) KIF18A
SCHEMBL30602280 0.86 KIF18A (0.70) KIF18A
SCHEMBL30522476 0.85 KIF18A (0.69) KIF18A
SCHEMBL31500852 0.85 KIF18A (0.68) KIF18A
SCHEMBL27457288 0.82 KIF18A (0.51) KIF18A
SCHEMBL30954003 0.82 KIF18A (0.51) KIF18A
SCHEMBL31500855 0.81 KIF18A (0.64) KIF18A
SCHEMBL22282373 0.81 KIF18A (0.75) KIF18A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116535400-B Azaspiro compounds and uses thereof 上海湃隆生物科技有限公司 2024-08-16 — — CN disclosed
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