Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPBWR1 | P48145 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | SCN10A | Q9Y5Y9 | 4/20 | 0.35 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.35 |
| ▸ | SELE | P16581 | 1/20 | 0.35 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.34 |
| ▸ | SCN1A | P35498 | 1/20 | 0.34 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.34 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.34 |
| ▸ | CCNC | P24863 | 1/20 | 0.34 |
| ▸ | CDK8 | P49336 | 1/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.34 |
| ▸ | FPR2 | P25090 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31065344 | 1.00 | NPBWR1 (0.35) | NPBWR1MCHR1SCN10AICAM1SELE | |
| SCHEMBL31065349 | 0.85 | EGFR (0.38) | MCHR1SCN10AICAM1SELEVCAM1 | |
| SCHEMBL31065386 | 0.80 | SCN5A (0.39) | NPBWR1MCHR1SCN10ASCN9AKCNH2 | |
| SCHEMBL31065370 | 0.77 | SCN5A (0.35) | SCN10ASCN9AKCNH2SCN5ASCN1A | |
| SCHEMBL5878919 | 0.73 | SLC6A4 (0.52) | SCN10ASCN9AKCNH2SCN5ASCN1A | |
| SCHEMBL5878557 | 0.73 | DHODH (0.43) | NPC1RAB9AL3MBTL1SMN1; SMN2MEN1 | |
| SCHEMBL189548 | 0.73 | PIK3CA (0.38) | P2RX3HRH4METKMT2A | |
| SCHEMBL5878875 | 0.72 | SLC6A2 (0.46) | SLC6A4SLC6A2NPC1RAB9AL3MBTL1 | |
| SCHEMBL189145 | 0.70 | GRM5 (0.38) | SLC6A2NPC1ALDH1A1SMN1; SMN2HRH4 | |
| SCHEMBL8160442 | 0.70 | GRM7 (0.40) | SCN10ASLC6A4SLC6A2SLC6A3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4602044-A1 | SUBSTITUTED 3,7-DIHYDRO-1 H-PURINE-2,6-DIONES AND USE THEREOF | invIOs GmbH (AT) | 2025-08-20 | — | — | EP | disclosed |
| WO-2024133605-A1 | SUBSTITUTED 3,7-DIHYDRO-1 H-PURINE-2,6-DIONES AND USE THEREOF | INVIOS GMBH (AT) | 2024-06-27 | — | — | WO | disclosed |