Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 10/20 | 0.58 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | PTGES | O14684 | 1/20 | 0.49 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.48 |
| ▸ | CCR5 | P51681 | 2/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31065357 | 1.00 | LRRK2 (0.58) | LRRK2FOLH1LMNAPOLBKDM4E | |
| SCHEMBL384896 | 0.86 | FOLH1 (0.68) | LRRK2FOLH1LMNAPOLBKDM4E | |
| SCHEMBL4723723 | 0.82 | LRRK2 (0.58) | LRRK2FOLH1LMNAPOLBKDM4E | |
| SCHEMBL30591972 | 0.82 | PTGDR2 (0.67) | LRRK2FOLH1LMNAPOLBKDM4E | |
| SCHEMBL6452235 | 0.82 | PTGDR2 (0.67) | LRRK2FOLH1LMNAPOLBKDM4E | |
| SCHEMBL552025 | 0.81 | LRRK2 (0.57) | LRRK2FOLH1LMNAPOLBKDM4E | |
| SCHEMBL9876914 | 0.81 | LRRK2 (0.59) | LRRK2FOLH1LMNAPOLBKDM4E | |
| SCHEMBL28260622 | 0.80 | LRRK2 (0.59) | LRRK2FOLH1LMNAPOLBKDM4E | |
| SCHEMBL5431545 | 0.80 | LRRK2 (0.63) | LRRK2FOLH1LMNAPOLBKDM4E | |
| SCHEMBL6492975 | 0.77 | LRRK2 (0.60) | LRRK2FOLH1LMNAPOLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4602044-A1 | SUBSTITUTED 3,7-DIHYDRO-1 H-PURINE-2,6-DIONES AND USE THEREOF | invIOs GmbH (AT) | 2025-08-20 | — | — | EP | disclosed |
| WO-2024133605-A1 | SUBSTITUTED 3,7-DIHYDRO-1 H-PURINE-2,6-DIONES AND USE THEREOF | INVIOS GMBH (AT) | 2024-06-27 | — | — | WO | disclosed |