Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.39 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 3/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PARK7 | Q99497 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21932498 | 1.00 | HDAC6 (0.41) | HDAC6POLBSTING1PTGER4PTGER2 | |
| SCHEMBL29428133 | 0.90 | HDAC6 (0.40) | HDAC6STING1HTR7PTGDR2KDM4E | |
| SCHEMBL21932239 | 0.88 | HDAC6 (0.41) | HDAC6POLBSTING1HTR7LMNA | |
| SCHEMBL31065604 | 0.88 | HDAC6 (0.41) | HDAC6POLBSTING1HTR7LMNA | |
| SCHEMBL23769015 | 0.87 | KMT2A (0.50) | HDAC6POLBMEN1HPGDKMT2A | |
| SCHEMBL21932306 | 0.82 | STING1 (0.61) | HDAC6STING1HTR7ALDH1A1MAPT | |
| SCHEMBL31065585 | 0.82 | STING1 (0.61) | HDAC6STING1HTR7ALDH1A1MAPT | |
| SCHEMBL21932165 | 0.80 | STING1 (0.49) | HDAC6STING1HTR7MAPT | |
| SCHEMBL29428023 | 0.80 | STING1 (0.49) | HDAC6STING1HTR7MAPT | |
| SCHEMBL28415044 | 0.79 | PTGER4 (0.39) | POLBSTING1PTGER4PTGER2HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111132972-B | Small molecule modulators of human STING | 克拉德夫制药有限公司 | 2024-07-12 | — | — | CN | disclosed |