Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 2/20 | 0.39 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.39 |
| ▸ | HTR7 | P34969 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MYC | P01106 | 3/20 | 0.34 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24295626 | 0.88 | ALDH1A1 (0.40) | HTR7LMNAPOLB | |
| SCHEMBL21932498 | 0.79 | HDAC6 (0.41) | PTGER4PTGER2HTR7LMNAP2RY14 | |
| SCHEMBL31065615 | 0.79 | HDAC6 (0.41) | PTGER4PTGER2HTR7LMNAP2RY14 | |
| SCHEMBL21932264 | 0.76 | PTGER4 (0.38) | PTGER4PTGER2HTR7LMNAP2RY14 | |
| SCHEMBL24296018 | 0.75 | PTGER4 (0.37) | PTGER4PTGER2HTR7LMNAP2RY14 | |
| SCHEMBL29428133 | 0.69 | HDAC6 (0.40) | HTR7STING1 | |
| SCHEMBL21932239 | 0.68 | HDAC6 (0.41) | HTR7LMNAPOLBSTING1 | |
| SCHEMBL31065604 | 0.68 | HDAC6 (0.41) | HTR7LMNAPOLBSTING1 | |
| SCHEMBL22043971 | 0.67 | STING1 (0.53) | HTR7LMNAPOLBSTING1 | |
| SCHEMBL29256235 | 0.67 | MAPT (0.43) | PTGER4PTGER2HTR7LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111132972-A | Small molecule modulators of human STING | 克拉德夫制药有限公司 | 2020-05-08 | — | — | CN | disclosed |