SCHEMBL31065657

SCHEMBL31065657

CCCCCCC(CC#N)CCCC

nearest known ligand 0.48

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.48
TSHR P16473 3/20 0.44
DNM1 Q05193 2/20 0.42
ALDH1A1 P00352 3/20 0.38
TDP1 Q9NUW8 1/20 0.38
CYP3A4 P08684 1/20 0.37
THRB P10828 1/20 0.36
CA2 P00918 1/20 0.36
OPRM1 P35372 1/20 0.36
FDPS P14324 3/20 0.34
GPR84 Q9NQS5 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10460696 0.98 LMNA (0.50) LMNATSHRDNM1ALDH1A1TDP1
SCHEMBL28191745 0.98 LMNA (0.50) LMNATSHRDNM1ALDH1A1TDP1
SCHEMBL14515882 0.98 LMNA (0.50) LMNATSHRDNM1ALDH1A1TDP1
SCHEMBL19135584 0.98 LMNA (0.50) LMNATSHRDNM1ALDH1A1TDP1
SCHEMBL28930080 0.98 LMNA (0.50) LMNATSHRDNM1ALDH1A1TDP1
SCHEMBL25121223 0.98 LMNA (0.50) LMNATSHRDNM1ALDH1A1TDP1
SCHEMBL764936 0.98 TSHR (0.46) LMNATSHRDNM1ALDH1A1TDP1
SCHEMBL366646 0.95 TSHR (0.48) LMNATSHRDNM1ALDH1A1TDP1
SCHEMBL30818337 0.93 LMNA (0.46) LMNATSHRDNM1THRBOPRM1
Boric Acid SCHEMBL28807350 0.90 LMNA (0.48) LMNATSHRALDH1A1CYP3A4FDPS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4712950-A2 IONIZABLE AMINE LIPIDS Intellia Therapeutics, Inc. (US) 2026-03-25 EP disclosed
WO-2024243031-A2 IONIZABLE AMINE LIPIDS INTELLIA THERAPEUTICS, INC. (US) 2024-11-28 WO disclosed
CN-118561684-A Synthesis method for preparing carbonyl chloride through cyano carburetion 中南大学 2024-08-30 CN disclosed