SCHEMBL31065680

SCHEMBL31065680

COC(=O)C1CCCN(c2ncnc3cc(Cl)ccc23)C1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRKDC P78527 5/20 0.53
CYP1A2 P05177 2/20 0.53
CYP2D6 P10635 1/20 0.53
ALDH1A1 P00352 3/20 0.52
MAPK1 P28482 2/20 0.52
KDM4E B2RXH2 2/20 0.52
NPC1 O15118 2/20 0.52
RAB9A P51151 2/20 0.52
HSD17B10 Q99714 2/20 0.52
TP53 P04637 1/20 0.52
CYP3A4 P08684 1/20 0.52
CYP2C9 P11712 1/20 0.52
HPGD P15428 1/20 0.52
CYP2C19 P33261 1/20 0.52
ATR Q13535 2/20 0.51
ATRIP Q8WXE1 2/20 0.51
PIK3CD O00329 1/20 0.49
PIK3CA P42336 1/20 0.49
PIK3CB P42338 1/20 0.49
PIK3CG P48736 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31065689 0.89 ALDH1A1 (0.66) PRKDCCYP1A2CYP2D6ALDH1A1MAPK1
SCHEMBL31065694 0.88 PRKDC (0.58) PRKDCCYP1A2ALDH1A1KDM4ENPC1
SCHEMBL31065687 0.88 PRKDC (0.53) PRKDCCYP1A2ALDH1A1MAPK1KDM4E
SCHEMBL17030833 0.86 PIK3CD (0.50) PRKDCCYP1A2ALDH1A1MAPK1KDM4E
SCHEMBL31065671 0.85 NPSR1 (0.53) PRKDCCYP1A2ALDH1A1MAPK1KDM4E
SCHEMBL31065672 0.83 PDE3A (0.61) MAPK1PDGFRBPDE3A
SCHEMBL31065678 0.82 PIK3CD (0.56) PRKDCCYP1A2ALDH1A1MAPK1KDM4E
SCHEMBL31065670 0.81 PIK3CD (0.55) PRKDCCYP1A2ALDH1A1MAPK1KDM4E
SCHEMBL31065685 0.81 PIK3CD (0.55) PRKDCCYP1A2ALDH1A1KDM4ENPC1
SCHEMBL31065679 0.81 ALDH1A1 (0.48) CYP1A2ALDH1A1MAPK1KDM4ENPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118561810-A Medicament for preventing and treating tea tree fungal diseases and preparation method thereof 贵州大学 2024-08-30 CN claimed
CN-118561810-A Medicament for preventing and treating tea tree fungal diseases and preparation method thereof 贵州大学 2024-08-30 CN disclosed