Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 3/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 11/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
| ▸ | TYK2 | P29597 | 1/20 | 0.35 |
| ▸ | JAK3 | P52333 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30968064 | 1.00 | CHRM1 (0.43) | CHRM1CHRM2CHRM3USP30GPR119 | |
| SCHEMBL30968074 | 0.79 | CHRM2 (0.41) | CHRM1CHRM2CHRM3USP30GPR119 | |
| SCHEMBL3522984 | 0.79 | CHRM2 (0.47) | CHRM1CHRM2CHRM3USP30GPR119 | |
| SCHEMBL30968057 | 0.78 | CHRM2 (0.42) | CHRM1CHRM2CHRM3USP30GPR119 | |
| SCHEMBL31065776 | 0.75 | GPR119 (0.32) | CHRM1CHRM2CHRM3USP30GPR119 | |
| SCHEMBL28554978 | 0.70 | CHRM2 (0.68) | CHRM1CHRM2CHRM3USP30GPR119 | |
| SCHEMBL21739027 | 0.70 | CHRM2 (0.68) | CHRM1CHRM2CHRM3USP30GPR119 | |
| SCHEMBL28554979 | 0.70 | CHRM2 (0.68) | CHRM1CHRM2CHRM3USP30GPR119 | |
| SCHEMBL14882620 | 0.70 | CHRM2 (0.68) | CHRM1CHRM2CHRM3USP30GPR119 | |
| SCHEMBL12094696 | 0.69 | CHRM2 (0.54) | CHRM1CHRM2CHRM3USP30GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024131942-A1 | CYCLOPROPANE TLR7 AND TLR8 INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF | 上海深势唯思科技有限责任公司 | 2024-06-27 | — | — | WO | disclosed |