Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | BTK | Q06187 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 2/20 | 0.35 |
| ▸ | APLNR | P35414 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31065777 | 1.00 | GAA (0.40) | GAAKMT2AMEN1MAPK1BTK | |
| SCHEMBL26342483 | 0.83 | MEN1 (0.42) | GAAKMT2AMEN1MAPK1BTK | |
| SCHEMBL15115795 | 0.83 | KMT2A (0.42) | GAAKMT2AMEN1MAPK1BTK | |
| SCHEMBL1730719 | 0.83 | KMT2A (0.42) | GAAKMT2AMEN1MAPK1BTK | |
| SCHEMBL31065768 | 0.83 | GAA (0.38) | GAAKMT2AMEN1MAPK1BTK | |
| SCHEMBL2087734 | 0.82 | RORC (0.43) | GAAKMT2AMEN1MAPK1BTK | |
| SCHEMBL10127311 | 0.82 | MEN1 (0.41) | GAAKMT2AMEN1MAPK1BTK | |
| SCHEMBL13485263 | 0.82 | MEN1 (0.41) | GAAKMT2AMEN1MAPK1BTK | |
| SCHEMBL13485258 | 0.82 | MEN1 (0.41) | GAAKMT2AMEN1MAPK1BTK | |
| SCHEMBL23299938 | 0.81 | MEN1 (0.40) | GAAKMT2AMEN1MAPK1BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024131942-A1 | CYCLOPROPANE TLR7 AND TLR8 INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF | 上海深势唯思科技有限责任公司 | 2024-06-27 | — | — | WO | disclosed |