Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | CCR6 | P51684 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 5/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.41 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.40 |
| ▸ | ESPL1 | Q14674 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31065888 | 1.00 | CYP1A2 (0.46) | CYP1A2TDP1ATMALDH1A1HIF1A | |
| SCHEMBL27275986 | 0.88 | CYP1A2 (0.46) | CYP1A2TDP1ATMALDH1A1HIF1A | |
| SCHEMBL1505782 | 0.85 | TDP1 (0.45) | CYP1A2TDP1ATMALDH1A1HIF1A | |
| SCHEMBL32659684 | 0.84 | ALDH1A1 (0.46) | CYP1A2TDP1ATMALDH1A1HIF1A | |
| SCHEMBL8112068 | 0.83 | TDP1 (0.44) | CYP1A2TDP1ATMALDH1A1HIF1A | |
| SCHEMBL18175845 | 0.83 | CYP1A2 (0.55) | CYP1A2TDP1ATMALDH1A1HIF1A | |
| SCHEMBL29237455 | 0.82 | TDP1 (0.46) | CYP1A2TDP1ATMALDH1A1HIF1A | |
| SCHEMBL30217347 | 0.82 | CYP1A2 (0.59) | CYP1A2TDP1ATMALDH1A1HIF1A | |
| SCHEMBL30217284 | 0.82 | TDP1 (0.46) | CYP1A2TDP1ATMALDH1A1HIF1A | |
| SCHEMBL27264780 | 0.82 | CYP1A2 (0.59) | CYP1A2TDP1ATMALDH1A1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4673139-A1 | NBD1 MODULATORS AND METHODS OF USING THE SAME | Sionna Therapeutics Inc. (US) | 2026-01-07 | — | — | EP | disclosed |
| WO-2024182742-A1 | NBD1 MODULATORS AND METHODS OF USING THE SAME | SIONNA THERAPEUTICS INC. (US) | 2024-09-06 | — | — | WO | disclosed |