Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K12 | Q12852 | 2/20 | 0.41 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 10/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 8/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL245771 | 0.72 | MAPT (0.61) | MAP3K12 | |
| SCHEMBL3169890 | 0.72 | HRH4 (0.65) | HRH3HRH4 | |
| SCHEMBL29762483 | 0.72 | MAPT (0.61) | MAP3K12 | |
| SCHEMBL31015574 | 0.71 | SMPD3 (0.45) | MAP3K12SMPD3HRH3 | |
| SCHEMBL22163202 | 0.71 | SMPD3 (0.49) | MAP3K12SMPD3HRH3 | |
| SCHEMBL30556697 | 0.70 | ATM (0.46) | MAP3K12 | |
| SCHEMBL31066184 | 0.69 | SMPD3 (0.34) | MAP3K12SMPD3HRH4 | |
| SCHEMBL21262341 | 0.68 | SMPD3 (0.42) | MAP3K12SMPD3 | |
| SCHEMBL30137174 | 0.68 | SMPD3 (0.42) | MAP3K12SMPD3 | |
| SCHEMBL3661086 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4673441-A1 | LZK INHIBITORS | Ureka Bioscienes, Inc. (US) | 2026-01-07 | — | — | EP | disclosed |
| WO-2024182552-A1 | LZK INHIBITORS | UEREKA BIOSCIENCES, INC. (US) | 2024-09-06 | — | — | WO | disclosed |