Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 2/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | PLAT | P00750 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | CDK9 | P50750 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15273696 | 0.75 | ALDH1A1 (0.41) | ALDH1A1KMT2ACYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL22275219 | 0.74 | ALDH1A1 (0.43) | ALDH1A1KMT2ACYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL21570102 | 0.73 | KDM4E (0.39) | ALDH1A1KDM4EHPGDNPC1MAPT | |
| SCHEMBL22275421 | 0.72 | ALDH1A1 (0.39) | ALDH1A1HPGDNPC1RAB9AKMT2A | |
| SCHEMBL31389508 | 0.72 | ALDH1A1 (0.42) | ALDH1A1KMT2ACYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL26089064 | 0.72 | HDAC6 (0.44) | ALDH1A1KDM4EKMT2ACYP1A2CYP2C19 | |
| SCHEMBL26093107 | 0.71 | PLAT (0.41) | ALDH1A1KDM4EHPGDKMT2ACYP1A2 | |
| SCHEMBL31389863 | 0.71 | ATM (0.43) | ALDH1A1MAPTKMT2ACYP1A2MEN1 | |
| SCHEMBL6383954 | 0.71 | USP2 (0.43) | ALDH1A1KDM4EHPGDNPC1RAB9A | |
| SCHEMBL31066473 | 0.70 | ALDH1A1 (0.38) | ALDH1A1KDM4EHPGDKMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024182447-A1 | COMPOUNDS AND METHODS FOR MODULATING RAS-PI3K | VIVIDION THERAPEUTICS, INC. (US) | 2024-09-06 | — | — | WO | disclosed |