Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7815895 | 0.93 | PPARG (0.81) | PPARGPPARA | |
| SCHEMBL7824139 | 0.92 | PPARG (0.83) | PPARGPPARA | |
| SCHEMBL8061173 | 0.92 | PPARG (0.74) | PPARGPPARA | |
| SCHEMBL7815781 | 0.91 | PPARG (1.00) | PPARGPPARA | |
| SCHEMBL7825493 | 0.91 | PPARG (0.73) | PPARGPPARA | |
| SCHEMBL9270271 | 0.91 | PPARG (0.76) | PPARGPPARA | |
| SCHEMBL7825955 | 0.91 | PPARG (0.73) | PPARGPPARA | |
| SCHEMBL9207919 | 0.91 | PPARG (0.84) | PPARGPPARA | |
| SCHEMBL7909717 | 0.90 | PPARG (0.80) | PPARGPPARA | |
| SCHEMBL7817262 | 0.90 | PPARG (0.75) | PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7803586-B2 | Chemical Process | ASTRAZENECA AB (SE) | 2010-09-28 | — | — | US | disclosed |
| US-20080115247-A1 | Chemical Process | ASTRAZENECA AB (SE) | 2008-05-15 | — | — | US | disclosed |
| EP-1828394-A2 | CHEMICAL PROCESS | AstraZeneca AB (SE) | 2007-09-05 | — | — | EP | disclosed |
| WO-2006064213-A2 | CHEMICAL PROCESS | ASTRAZENECA AB (SE) | 2006-06-22 | — | — | WO | disclosed |
| US-6743608-B2 | GENERATION OF PREFERENTIAL ENANTIOMERS; OBTAIN SUBSTRATE, INCUBATE WITH ENZYME, RECOVER PRODUCT | NOVO NORDISK PHARMACEUTICALS, INC. (DK) | 2004-06-01 | — | — | US | disclosed |
| US-20030008361-A1 | Process for the preparation of substituted 3-phenyl-propanoic acid esters and substituted 3-phenyl-propanoic acids | EBDRUP SOREN (DK) | 2003-01-09 | — | — | US | disclosed |
| EP-1206565-A1 | PROCESS FOR THE PREPARATION OF SUBSTITUTED 3-PHENYL-PROPANOIC ACID ESTERS AND SUBSTITUTED 3-PHENYL-PROPANOIC ACIDS | NOVO NORDISK A/S (DK) | 2002-05-22 | — | — | EP | disclosed |
| EP-0648212-B1 | BENZOXAZOLE AND BENZOTHIAZOLE DERIVATIVES AS PHARMACEUTICAL | SMITHKLINE BEECHAM PLC (GB) | 2001-10-24 | — | — | EP | disclosed |
| WO-2001011073-A1 | PROCESS FOR THE PREPARATION OF SUBSTITUTED 3-PHENYL-PROPANOIC ACID ESTERS AND SUBSTITUTED 3-PHENYL-PROPANOIC ACIDS | NOVO NORDISK A/S (DK) | 2001-02-15 | — | — | WO | disclosed |
| WO-2001011072-A1 | PROCESS FOR THE PREPARATION OF SUBSTITUTED 3-PHENYL-PROPANOIC ACID ESTERS AND SUBSTITUTED 3-PHENYL-PROPANOIC ACIDS | NOVO NORDISK A/S (DK) | 2001-02-15 | — | — | WO | disclosed |
| EP-1000938-A1 | Heterocyclic compounds as pharmaceuticals | SMITHKLINE BEECHAM PLC (GB) | 2000-05-17 | — | — | EP | disclosed |
| US-6048883-A | HYPOGLYCEMIC AGENT | SMITHKLINE BEECHAM P.L.C. (GB) | 2000-04-11 | — | — | US | disclosed |
| EP-0648212-A1 | HETEROCYCLIC COMPOUNDS AS PHARMACEUTICAL | SMITHKLINE BEECHAM PLC (GB) | 1995-04-19 | — | — | EP | disclosed |
| WO-1994001420-A1 | HETEROCYCLIC COMPOUNDS AS PHARMACEUTICAL | SMITHKLINE BEECHAM PLC (GB) | 1994-01-20 | — | — | WO | disclosed |