SCHEMBL7909717

SCHEMBL7909717

COC(=O)C(Cc1ccc(OCCN(C)c2nc3ccccc3o2)cc1)C(=O)OC

nearest known ligand 0.80

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PPARG P37231 20/20 0.80
PPARA Q07869 2/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9389120 0.95 PPARG (0.76) PPARGPPARA
SCHEMBL9393956 0.91 PPARG (0.74) PPARGPPARA
SCHEMBL7824971 0.91 PPARG (0.78) PPARGPPARA
SCHEMBL7920689 0.90 PPARG (0.77) PPARGPPARA
SCHEMBL3106722 0.90 PPARG (0.84) PPARGPPARA
SCHEMBL9084397 0.90 PPARG (0.77) PPARGPPARA
SCHEMBL9087444 0.90 PPARG (0.77) PPARGPPARA
SCHEMBL7824382 0.90 PPARG (0.77) PPARGPPARA
SCHEMBL9087533 0.90 PPARG (0.82) PPARGPPARA
SCHEMBL9288468 0.90 PPARG (0.76) PPARGPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6204277-B1 TREATING DIABETES JAPAN TOBACCO INC. (JP) 2001-03-20 US disclosed
EP-0930299-A1 PROPIONIC ACID DERIVATIVES AND APPLICATIONS THEREOF Japan Tobacco Inc. (JP) 1999-07-21 EP disclosed