SCHEMBL31067280

SCHEMBL31067280

O=[N+]([O-])c1ccc2ncc(F)cc2c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.54
CYP3A4 P08684 2/20 0.46
NAMPT P43490 1/20 0.46
XDH P47989 1/20 0.46
MAPT P10636 2/20 0.45
POLB P06746 1/20 0.45
MAOB P27338 1/20 0.45
NOS1 P29475 1/20 0.45
TXNRD1 Q16881 1/20 0.45
TXNRD3 Q86VQ6 1/20 0.45
TXNRD2 Q9NNW7 1/20 0.45
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
HIF1A Q16665 1/20 0.43
TDP1 Q9NUW8 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
TSHR P16473 1/20 0.43
HTT P42858 1/20 0.43
PDGFRB P09619 1/20 0.43
PDGFRA P16234 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31067264 0.87 ALDH1A1 (0.50) ALDH1A1CYP3A4NAMPTXDHMAPT
SCHEMBL28110970 0.87 ALDH1A1 (0.63) ALDH1A1CYP3A4NAMPTXDHMAPT
SCHEMBL4816985 0.80 ALDH1A1 (0.54) ALDH1A1CYP3A4NAMPTXDHMAPT
SCHEMBL28811214 0.80 ALDH1A1 (0.54) ALDH1A1CYP3A4NAMPTXDHMAPT
SCHEMBL16289375 0.80 ALDH1A1 (0.54) ALDH1A1CYP3A4NAMPTXDHMAPT
SCHEMBL14906745 0.80 ALDH1A1 (0.54) ALDH1A1CYP3A4NAMPTXDHMAPT
SCHEMBL7473834 0.80 ALDH1A1 (0.54) ALDH1A1CYP3A4NAMPTXDHMAPT
SCHEMBL10762975 0.80 ALDH1A1 (0.54) ALDH1A1CYP3A4NAMPTXDHMAPT
SCHEMBL27920418 0.77 ALDH1A1 (0.46) ALDH1A1CYP3A4NAMPTXDHMAPT
SCHEMBL14906648 0.76 ALDH1A1 (0.58) ALDH1A1MAPTMEN1KMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118496154-A Quinoline group-containing triptycene diamine monomer, polymer and preparation method 吉林大学 2024-08-16 CN disclosed