Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 14/20 | 0.57 |
| ▸ | CARM1 | Q86X55 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | F9 | P00740 | 2/20 | 0.46 |
| ▸ | F10 | P00742 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18605077 | 1.00 | KLKB1 (0.57) | KLKB1CARM1TP53MAPTSMN1; SMN2 | |
| SCHEMBL31067428 | 0.91 | KLKB1 (0.64) | KLKB1CARM1F9F10 | |
| SCHEMBL18604889 | 0.91 | KLKB1 (0.64) | KLKB1CARM1F9F10 | |
| SCHEMBL17064530 | 0.85 | KLKB1 (0.64) | KLKB1CARM1 | |
| SCHEMBL17064893 | 0.84 | KLKB1 (0.56) | KLKB1CARM1F10 | |
| SCHEMBL31067643 | 0.84 | KLKB1 (0.54) | KLKB1CARM1 | |
| SCHEMBL31067563 | 0.84 | KLKB1 (0.56) | KLKB1CARM1F10 | |
| SCHEMBL17064358 | 0.84 | KLKB1 (0.54) | KLKB1CARM1 | |
| SCHEMBL29825870 | 0.83 | KLKB1 (0.53) | KLKB1 | |
| SCHEMBL18604718 | 0.83 | KLKB1 (0.53) | KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113307772-B | Human plasma kallikrein inhibitors | 拜奥克里斯特制药公司 | 2024-06-28 | — | — | CN | disclosed |