Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 18/20 | 0.54 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.47 |
| ▸ | PLG | P00747 | 1/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17064358 | 1.00 | KLKB1 (0.54) | KLKB1CARM1PLGPRSS1PRSS2 | |
| SCHEMBL31067563 | 0.86 | KLKB1 (0.56) | KLKB1CARM1PLGPRSS1PRSS2 | |
| SCHEMBL17064893 | 0.86 | KLKB1 (0.56) | KLKB1CARM1PLGPRSS1PRSS2 | |
| SCHEMBL31067486 | 0.84 | KLKB1 (0.57) | KLKB1CARM1 | |
| SCHEMBL18605077 | 0.84 | KLKB1 (0.57) | KLKB1CARM1 | |
| SCHEMBL17064543 | 0.84 | KLKB1 (0.54) | KLKB1PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL31067479 | 0.84 | KLKB1 (0.54) | KLKB1PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL31067599 | 0.84 | KLKB1 (0.56) | KLKB1CARM1PLGPRSS1PRSS2 | |
| SCHEMBL18605064 | 0.84 | KLKB1 (0.56) | KLKB1CARM1PLGPRSS1PRSS2 | |
| SCHEMBL17064530 | 0.83 | KLKB1 (0.64) | KLKB1CARM1PLGPRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4663636-A2 | TRIFLUOROMETHYL SUBSTITUTED PYRAZOLES AS HUMAN PLASMA KALLIKREIN INHIBITORS | BioCryst Pharmaceuticals, Inc. (US) | 2025-12-17 | — | — | EP | disclosed |
| CN-113307772-B | Human plasma kallikrein inhibitors | 拜奥克里斯特制药公司 | 2024-06-28 | — | — | CN | disclosed |