Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 13/20 | 1.00 |
| ▸ | PRSS1 | P07477 | 9/20 | 1.00 |
| ▸ | PRSS2 | P07478 | 9/20 | 1.00 |
| ▸ | PRSS3 | P35030 | 9/20 | 1.00 |
| ▸ | F2 | P00734 | 9/20 | 1.00 |
| ▸ | F9 | P00740 | 2/20 | 1.00 |
| ▸ | PROC | P04070 | 2/20 | 1.00 |
| ▸ | KLK1 | P06870 | 1/20 | 1.00 |
| ▸ | KLKB1 | P03952 | 4/20 | 0.98 |
| ▸ | CFH | P08603 | 1/20 | 0.98 |
| ▸ | CARM1 | Q86X55 | 3/20 | 0.84 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29825652 | 1.00 | F10 (1.00) | F10PRSS1PRSS2PRSS3F2 | |
| SCHEMBL3052253 | 1.00 | F10 (1.00) | F10PRSS1PRSS2PRSS3F2 | |
| Hydrochloric Acid SCHEMBL29377504 | 0.99 | F10 (1.00) | F10PRSS1PRSS2PRSS3F2 | |
| SCHEMBL7742478 | 0.94 | F10 (0.89) | F10PRSS1PRSS2PRSS3F2 | |
| SCHEMBL13550922 | 0.93 | F10 (1.00) | F10PRSS1PRSS2PRSS3F2 | |
| SCHEMBL7749603 | 0.92 | PRSS1 (0.88) | F10PRSS1PRSS2PRSS3F2 | |
| SCHEMBL19706432 | 0.91 | F10 (0.83) | F10PRSS1PRSS2PRSS3F2 | |
| SCHEMBL14565397 | 0.89 | CARM1 (1.00) | F10PRSS1PRSS2PRSS3F2 | |
| SCHEMBL14565395 | 0.89 | CARM1 (1.00) | F10PRSS1PRSS2PRSS3F2 | |
| SCHEMBL3833378 | 0.86 | F10 (0.80) | F10PRSS1PRSS2PRSS3F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4663636-A2 | TRIFLUOROMETHYL SUBSTITUTED PYRAZOLES AS HUMAN PLASMA KALLIKREIN INHIBITORS | BioCryst Pharmaceuticals, Inc. (US) | 2025-12-17 | — | — | EP | disclosed |
| CN-113307772-B | Human plasma kallikrein inhibitors | 拜奥克里斯特制药公司 | 2024-06-28 | — | — | CN | disclosed |