Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 15/20 | 0.83 |
| ▸ | PRSS1 | P07477 | 8/20 | 0.83 |
| ▸ | PRSS2 | P07478 | 8/20 | 0.83 |
| ▸ | PRSS3 | P35030 | 8/20 | 0.83 |
| ▸ | F2 | P00734 | 8/20 | 0.83 |
| ▸ | F9 | P00740 | 2/20 | 0.83 |
| ▸ | PROC | P04070 | 2/20 | 0.83 |
| ▸ | KLK1 | P06870 | 1/20 | 0.83 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.82 |
| ▸ | CFH | P08603 | 1/20 | 0.82 |
| ▸ | CARM1 | Q86X55 | 4/20 | 0.82 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3052253 | 0.91 | F10 (1.00) | F10PRSS1PRSS2PRSS3F2 | |
| SCHEMBL29825652 | 0.91 | F10 (1.00) | F10PRSS1PRSS2PRSS3F2 | |
| SCHEMBL31067656 | 0.91 | F10 (1.00) | F10PRSS1PRSS2PRSS3F2 | |
| Hydrochloric Acid SCHEMBL29377504 | 0.90 | F10 (1.00) | F10PRSS1PRSS2PRSS3F2 | |
| SCHEMBL14565395 | 0.89 | CARM1 (1.00) | F10PRSS1PRSS2PRSS3F2 | |
| SCHEMBL14565397 | 0.89 | CARM1 (1.00) | F10PRSS1PRSS2PRSS3F2 | |
| SCHEMBL7742478 | 0.85 | F10 (0.89) | F10PRSS1PRSS2PRSS3F2 | |
| SCHEMBL13550922 | 0.84 | F10 (1.00) | F10PRSS1PRSS2PRSS3F2 | |
| SCHEMBL7749603 | 0.83 | PRSS1 (0.88) | F10PRSS1PRSS2PRSS3F2 | |
| SCHEMBL8163627 | 0.81 | F10 (0.80) | F10PRSS1PRSS2PRSS3F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170354723-A1 | COMPOSITIONS AND METHODS FOR CELL TRANSPLANTATION | PROMETHERA BIOSCIENCES S.A. (BE) | 2017-12-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170354723-A1 | COMPOSITIONS AND METHODS FOR CELL TRANSPLANTATION | SERPINC1, F13B, F12 | F10 7/4885PRSS1 171/4885PRSS2 209/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.