Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | RAD52 | P43351 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
| ▸ | CPN1 | P15169 | 1/20 | 0.36 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.36 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.36 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17064367 | 1.00 | POLB (0.40) | POLBMAPTPKMRAD52TAAR1 | |
| SCHEMBL14124778 | 0.84 | ADORA2A (0.51) | POLBMAPTPKMRAD52TAAR1 | |
| SCHEMBL31067482 | 0.83 | ADRA2A (0.46) | CA1CA2CA9CTDSP1ALDH1A1 | |
| SCHEMBL17064760 | 0.83 | ADRA2A (0.46) | CA1CA2CA9CTDSP1ALDH1A1 | |
| SCHEMBL17064366 | 0.81 | PARP1 (0.42) | POLBMAPTPKMRAD52TAAR1 | |
| SCHEMBL597897 | 0.80 | TRPM4 (0.52) | POLBMAPTPKMRAD52TAAR1 | |
| SCHEMBL4073301 | 0.74 | CA1 (0.58) | CA1CA2CA9CPN1CPB2 | |
| SCHEMBL22394364 | 0.74 | CA1 (0.37) | ADORA2AADORA1CA1CA2CA9 | |
| SCHEMBL23119534 | 0.73 | CA1 (0.39) | ADORA2AADORA1CA1CA2CA9 | |
| SCHEMBL17064895 | 0.73 | IDO1 (0.46) | MAPTCA1CA2CA9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113307772-B | Human plasma kallikrein inhibitors | 拜奥克里斯特制药公司 | 2024-06-28 | — | — | CN | disclosed |