Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRA | P16234 | 13/20 | 0.74 |
| ▸ | KDR | P35968 | 14/20 | 0.62 |
| ▸ | EGFR | P00533 | 4/20 | 0.57 |
| ▸ | GAK | O14976 | 2/20 | 0.57 |
| ▸ | KIT | P10721 | 1/20 | 0.53 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.53 |
| ▸ | EPHB6 | O15197 | 1/20 | 0.53 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.53 |
| ▸ | ABL1 | P00519 | 1/20 | 0.53 |
| ▸ | LCK | P06239 | 1/20 | 0.53 |
| ▸ | SRC | P12931 | 1/20 | 0.53 |
| ▸ | EPHA1 | P21709 | 1/20 | 0.53 |
| ▸ | EPHA8 | P29322 | 1/20 | 0.53 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.53 |
| ▸ | MAP2K5 | Q13163 | 1/20 | 0.53 |
| ▸ | COQ8A | Q8NI60 | 1/20 | 0.53 |
| ▸ | NLK | Q9UBE8 | 1/20 | 0.53 |
| ▸ | HTR2C | P28335 | 1/20 | 0.52 |
| ▸ | HTR2B | P41595 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31067620 | 0.91 | PDGFRA (0.78) | PDGFRAKDREGFRGAKBMPR1B | |
| SCHEMBL31067675 | 0.89 | KDR (0.75) | PDGFRAKDREGFRGAKKIT | |
| SCHEMBL31067626 | 0.88 | PDGFRA (0.81) | PDGFRAKDREGFRGAKKIT | |
| SCHEMBL31067654 | 0.88 | PDGFRA (0.75) | PDGFRAKDREGFR | |
| SCHEMBL31067659 | 0.88 | PDGFRA (0.74) | PDGFRAKDREGFRHTR2CHTR2B | |
| SCHEMBL31067604 | 0.88 | PDGFRA (0.74) | PDGFRAKDREGFRGAKBMPR1B | |
| SCHEMBL31067686 | 0.86 | EGFR (0.76) | PDGFRAKDREGFRGAKKIT | |
| SCHEMBL31067639 | 0.85 | PDGFRA (1.00) | PDGFRAKDREGFRGAKBMPR1B | |
| SCHEMBL31067687 | 0.85 | PDGFRA (0.83) | PDGFRAKDREGFRGAKBMPR1B | |
| SCHEMBL31067691 | 0.85 | KDR (0.79) | KDREGFRKIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118530175-A | PDGFR inhibitor and preparation method and application thereof | 中国药科大学 | 2024-08-23 | — | — | CN | disclosed |