Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 6/20 | 0.76 |
| ▸ | GAK | O14976 | 2/20 | 0.76 |
| ▸ | PDGFRA | P16234 | 8/20 | 0.74 |
| ▸ | KDR | P35968 | 13/20 | 0.72 |
| ▸ | KIT | P10721 | 2/20 | 0.72 |
| ▸ | RAF1 | P04049 | 1/20 | 0.64 |
| ▸ | MET | P08581 | 1/20 | 0.64 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.64 |
| ▸ | SRC | P12931 | 1/20 | 0.64 |
| ▸ | FLT1 | P17948 | 1/20 | 0.64 |
| ▸ | FLT4 | P35916 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31067626 | 0.91 | PDGFRA (0.81) | EGFRGAKPDGFRAKDRKIT | |
| SCHEMBL31067677 | 0.89 | PDGFRA (0.75) | EGFRGAKPDGFRAKDRKIT | |
| SCHEMBL31067716 | 0.89 | PDGFRA (0.82) | EGFRGAKPDGFRAKDRRAF1 | |
| SCHEMBL31067698 | 0.88 | KDR (0.74) | EGFRGAKPDGFRAKDR | |
| SCHEMBL31067717 | 0.88 | PDGFRA (0.74) | EGFRGAKPDGFRAKDRKIT | |
| SCHEMBL31067739 | 0.88 | PDGFRA (0.74) | EGFRGAKPDGFRAKDR | |
| SCHEMBL31031038 | 0.87 | EGFR (1.00) | EGFRGAKKDRSRC | |
| SCHEMBL31067682 | 0.86 | PDGFRA (0.74) | EGFRGAKPDGFRAKDRKIT | |
| SCHEMBL31067687 | 0.85 | PDGFRA (0.83) | EGFRGAKPDGFRAKDRSRC | |
| SCHEMBL31067639 | 0.85 | PDGFRA (1.00) | EGFRGAKPDGFRAKDRSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118530175-A | PDGFR inhibitor and preparation method and application thereof | 中国药科大学 | 2024-08-23 | — | — | CN | disclosed |