Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 13/20 | 0.74 |
| ▸ | PDGFRA | P16234 | 12/20 | 0.74 |
| ▸ | EGFR | P00533 | 3/20 | 0.62 |
| ▸ | GAK | O14976 | 1/20 | 0.57 |
| ▸ | BRAF | P15056 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31067663 | 0.91 | PDGFRA (0.81) | KDRPDGFRAEGFRGAK | |
| SCHEMBL31067677 | 0.89 | PDGFRA (0.75) | KDRPDGFRAEGFRGAKMAPT | |
| SCHEMBL31067716 | 0.89 | PDGFRA (0.82) | KDRPDGFRAEGFRGAKBRAF | |
| SCHEMBL31067717 | 0.88 | PDGFRA (0.74) | KDRPDGFRAEGFRGAK | |
| SCHEMBL31067686 | 0.88 | EGFR (0.76) | KDRPDGFRAEGFRGAK | |
| SCHEMBL31067739 | 0.88 | PDGFRA (0.74) | KDRPDGFRAEGFRGAK | |
| SCHEMBL31067696 | 0.88 | PDGFRA (0.77) | KDRPDGFRAEGFRGAKKDM4E | |
| SCHEMBL12484448 | 0.87 | EGFR (0.73) | KDRPDGFRAEGFRGAKKDM4E | |
| SCHEMBL31067659 | 0.86 | PDGFRA (0.74) | KDRPDGFRAEGFR | |
| SCHEMBL31067687 | 0.85 | PDGFRA (0.83) | KDRPDGFRAEGFRGAK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118530175-A | PDGFR inhibitor and preparation method and application thereof | 中国药科大学 | 2024-08-23 | — | — | CN | disclosed |