Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | LIG1 | P18858 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29348941 | 0.85 | MMP13 (0.43) | MMP13FAAHMGLLPOLBHPGD | |
| SCHEMBL29349005 | 0.84 | MMP13 (0.56) | MMP13FAAHMGLLLIG1POLB | |
| SCHEMBL29348793 | 0.81 | MMP13 (0.53) | MMP13FAAHMGLLLIG1POLB | |
| SCHEMBL29348930 | 0.76 | MMP13 (0.59) | MMP13FAAHMGLLPOLBMMP2 | |
| SCHEMBL29348936 | 0.75 | MMP13 (0.40) | MMP13FAAHMGLLLIG1POLB | |
| SCHEMBL29348881 | 0.71 | MMP13 (0.57) | MMP13FAAHMGLLPOLBHPGD | |
| SCHEMBL29348858 | 0.71 | MMP13 (0.54) | MMP13FAAHMGLLPOLBMMP2 | |
| SCHEMBL29348882 | 0.70 | MMP13 (0.56) | MMP13FAAHMGLLPOLBMMP2 | |
| SCHEMBL31641986 | 0.69 | GRM5 (0.41) | MMP13RXFP1 | |
| SCHEMBL29348909 | 0.69 | MMP13 (0.51) | MMP13FAAHMGLLPOLBHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4648853-A1 | TARGETED DEGRADATION OF VAV1 | Monte Rosa Therapeutics AG (CH) | 2025-11-19 | — | — | EP | disclosed |
| WO-2024151547-A1 | TARGETED DEGRADATION OF VAV1 | MONTE ROSA THERAPEUTICS, INC. (US) | 2024-07-18 | — | — | WO | disclosed |