SCHEMBL31068532

SCHEMBL31068532

CC(C)(C)OC(=O)c1cccc(C2CCCCNC2=O)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 1/20 0.40
PDE4A P27815 1/20 0.39
PDE4B Q07343 1/20 0.39
PDE4C Q08493 1/20 0.39
PDE4D Q08499 1/20 0.39
SLC7A5 Q01650 1/20 0.38
CCR2 P41597 3/20 0.37
DDB1 Q16531 2/20 0.37
CRBN Q96SW2 2/20 0.37
RAB9A P51151 2/20 0.37
NPC1 O15118 1/20 0.37
KMO O15229 1/20 0.36
FNTA P49354 1/20 0.36
FNTB P49356 1/20 0.36
PGGT1B P53609 1/20 0.36
TP53 P04637 1/20 0.36
GABRA1 P14867 1/20 0.36
GABRG2 P18507 1/20 0.36
GABRB3 P28472 1/20 0.36
GABRA3 P34903 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29346862 1.00 KDM1A (0.40) KDM1APDE4APDE4BPDE4CPDE4D
SCHEMBL31068587 0.83 CRBN (0.50) SLC7A5DDB1CRBNNPC1TP53
SCHEMBL7679191 0.74 PDE4A (0.41) PDE4APDE4BPDE4CPDE4DDDB1
SCHEMBL7678953 0.74 DDB1 (0.61) PDE4APDE4BPDE4CPDE4DDDB1
SCHEMBL29346871 0.73 PDE4A (0.44) KDM1APDE4APDE4BPDE4CPDE4D
SCHEMBL13026715 0.71 PARP1 (0.59) KDM1ASLC7A5KMOGABRA1GABRG2
SCHEMBL28147155 0.70 DDB1 (0.51) PDE4APDE4BPDE4CPDE4DDDB1
SCHEMBL32677547 0.70 SLC7A5 (0.45) KDM1ASLC7A5KMOGABRA1GABRG2
SCHEMBL32677546 0.70 SLC7A5 (0.45) KDM1ASLC7A5KMOGABRA1GABRG2
SCHEMBL110296 0.70 SLC7A5 (0.58) SLC7A5GABRA1GABRG2GABRB3GABRA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4650348-A1 CEREBLON E3 LIGASE BINDING COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND PRODUCTION METHOD THEREFOR Mitsubishi Tanabe Pharma Corporation (JP) 2025-11-19 EP disclosed
WO-2024150815-A1 CEREBLON E3 LIGASE BINDING COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND PRODUCTION METHOD THEREFOR 田辺三菱製薬株式会社 2024-07-18 WO disclosed