Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.40 |
| ▸ | FNTA | P49354 | 1/20 | 0.38 |
| ▸ | FNTB | P49356 | 1/20 | 0.38 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TYK2 | P29597 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.35 |
| ▸ | CCR2 | P41597 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29346872 | 0.81 | CRBN (0.56) | DDB1CRBN | |
| SCHEMBL7678953 | 0.80 | DDB1 (0.61) | PDE4APDE4BPDE4CPDE4DDDB1 | |
| SCHEMBL7679191 | 0.78 | PDE4A (0.41) | PDE4APDE4BPDE4CPDE4DDDB1 | |
| SCHEMBL28147155 | 0.74 | DDB1 (0.51) | PDE4APDE4BPDE4CPDE4DDDB1 | |
| SCHEMBL31068532 | 0.73 | KDM1A (0.40) | PDE4APDE4BPDE4CPDE4DDDB1 | |
| SCHEMBL29346862 | 0.73 | KDM1A (0.40) | PDE4APDE4BPDE4CPDE4DDDB1 | |
| SCHEMBL31730010 | 0.71 | LMNA (0.48) | SMN1; SMN2ALDH1A1KDM4EKMT2A | |
| SCHEMBL21805277 | 0.71 | POLB (0.45) | PDE4APDE4BPDE4CPDE4DDDB1 | |
| SCHEMBL11254018 | 0.70 | KCNH2 (0.50) | DDB1CRBNFNTAFNTBPGGT1B | |
| SCHEMBL27351818 | 0.70 | DDB1 (0.66) | PDE4APDE4BPDE4CPDE4DDDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024150815-A1 | CEREBLON E3 LIGASE BINDING COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND PRODUCTION METHOD THEREFOR | 田辺三菱製薬株式会社 | 2024-07-18 | — | — | WO | disclosed |