Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 4/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | GBA1 | P04062 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25263568 | 1.00 | AOC3 (0.46) | AOC3TAAR1HTR2AHRH1SLC6A2 | |
| SCHEMBL8722245 | 0.83 | TAAR1 (0.49) | TAAR1HTR2AHRH1SLC6A2SLC6A4 | |
| SCHEMBL25833084 | 0.80 | GBA1 (0.45) | AOC3TAAR1HTR2AHRH1TDP1 | |
| SCHEMBL8439197 | 0.80 | SLC22A1 (0.59) | AOC3HTR2AHRH1SLC6A2SLC6A4 | |
| SCHEMBL6493022 | 0.80 | AOC3 (0.51) | AOC3TAAR1HTR2AHRH1SLC6A2 | |
| SCHEMBL24951572 | 0.80 | SLC22A1 (0.59) | AOC3HTR2AHRH1SLC6A2SLC6A4 | |
| SCHEMBL6491746 | 0.80 | SLC22A1 (0.59) | AOC3HTR2AHRH1SLC6A2SLC6A4 | |
| SCHEMBL28168731 | 0.80 | MEN1 (0.54) | AOC3TAAR1DNM1SMN1; SMN2SLC18A3 | |
| SCHEMBL31138108 | 0.79 | LMNA (0.57) | SLC6A2SLC6A4SLC6A3MAPTSLC18A3 | |
| SCHEMBL6683467 | 0.79 | LMNA (0.57) | SLC6A2SLC6A4SLC6A3MAPTSLC18A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118541370-A | Azaindole derivatives and their use as ERK kinase inhibitors | AGV探索公司 | 2024-08-23 | — | — | CN | disclosed |