SCHEMBL31069367

SCHEMBL31069367

NCc1ccc2c(c1)nc(Cn1c(=O)n(CC(F)(F)F)c3ccc(F)cc31)n2CCCCF

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31069251 0.94 CYP3A4 (0.37)
SCHEMBL31069407 0.90
SCHEMBL31069390 0.90 AGTR1 (0.39)
SCHEMBL31069436 0.89 TBXA2R (0.37)
SCHEMBL31069326 0.88
SCHEMBL31069344 0.88 CNR2 (0.39)
SCHEMBL31069308 0.88 CYP3A4 (0.43)
SCHEMBL31069307 0.87 AGTR1 (0.39)
SCHEMBL31069406 0.86 AGTR1 (0.38)
SCHEMBL6242827 0.85 MEN1 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024174953-A1 BENZIMIDAZOLE DERIVATIVE AND MEDICAL USE THEREOF 苏州隆博泰药业有限公司 2024-08-29 WO claimed
WO-2024174953-A1 BENZIMIDAZOLE DERIVATIVE AND MEDICAL USE THEREOF 苏州隆博泰药业有限公司 2024-08-29 WO disclosed