Olomoucine Ii

Olomoucine Ii

SCHEMBL31069520

CCC(CO)Nc1nc(NCc2ccccc2O)c2ncn(C(C)C)c2n1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDK2 P24941 16/20 1.00
CCNE1 P24864 14/20 1.00
CDK1 P06493 10/20 1.00
CDK9 P50750 8/20 1.00
CCNB1 P14635 8/20 1.00
CDK5 Q00535 7/20 1.00
CCNT1 O60563 6/20 1.00
CCNB2 O95067 6/20 1.00
CCNB3 Q8WWL7 6/20 1.00
CDK5R1 Q15078 5/20 1.00
CACNA1B Q00975 2/20 1.00
CCNE2 O96020 3/20 0.79
CCNT2 O60583 1/20 0.79
CDK7 P50613 5/20 0.78
CDK4 P11802 3/20 0.78
CCND1 P24385 3/20 0.78
MAPK1 P28482 3/20 0.78
CCNH P51946 3/20 0.78
CCNK O75909 3/20 0.78
CDK12 Q9NYV4 3/20 0.78

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Olomoucine Ii SCHEMBL786673 1.00 CDK2 (1.00) CDK2CCNE1CDK1CDK9CCNB1
Olomoucine Ii SCHEMBL3514137 1.00 CDK2 (1.00) CDK2CCNE1CDK1CDK9CCNB1
SCHEMBL1352423 0.90 CDK2 (0.81) CDK2CCNE1CDK1CDK9CCNB1
SCHEMBL15117753 0.88 CDK2 (0.80) CDK2CCNE1CDK1CDK9CCNB1
SCHEMBL1441193 0.88 CDK2 (0.85) CDK2CCNE1CDK1CDK9CCNB1
SCHEMBL15118130 0.88 CDK2 (1.00) CDK2CCNE1CDK1CDK9CCNB1
(Rs)-Roscovitine SCHEMBL172593 0.87 CDK1 (1.00) CDK2CCNE1CDK1CDK9CCNB1
(S)-Roscovitine SCHEMBL2907488 0.87 CDK1 (1.00) CDK2CCNE1CDK1CDK9CCNB1
Seliciclib SCHEMBL94728 0.87 CDK1 (1.00) CDK2CCNE1CDK1CDK9CCNB1
(Rs)-Roscovitine SCHEMBL15163619 0.87 CDK1 (1.00) CDK2CCNE1CDK1CDK9CCNB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240252688-A1 COMPOSITIONS AND METHODS FOR ENHANCED PROTEIN PRODUCTION HDT BIO CORP. 2024-08-01 US disclosed