Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 2/20 | 0.53 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.53 |
| ▸ | RYR2 | Q92736 | 1/20 | 0.53 |
| ▸ | NTRK2 | Q16620 | 2/20 | 0.51 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.51 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.51 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.51 |
| ▸ | KDR | P35968 | 3/20 | 0.50 |
| ▸ | METAP1 | P53582 | 3/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | JAK2 | O60674 | 1/20 | 0.50 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.50 |
| ▸ | MET | P08581 | 1/20 | 0.50 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.50 |
| ▸ | PRKACA | P17612 | 1/20 | 0.50 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.50 |
| ▸ | FLT3 | P36888 | 1/20 | 0.50 |
| ▸ | GSK3B | P49841 | 1/20 | 0.50 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.50 |
| ▸ | MST1R | Q04912 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2849831 | 1.00 | PDE3B (0.53) | PDE3BPDE3ARYR2NTRK2CLK4 | |
| SCHEMBL10113037 | 0.88 | CLK4 (0.47) | PDE3BPDE3ARYR2NTRK2CLK4 | |
| SCHEMBL2023021 | 0.86 | PDE3B (0.57) | PDE3BPDE3ARYR2CLK4KDR | |
| SCHEMBL26785931 | 0.85 | PDE3B (0.53) | PDE3BPDE3ARYR2CLK4KDR | |
| SCHEMBL30629139 | 0.85 | PDE3B (0.53) | PDE3BPDE3ARYR2CLK4KDR | |
| SCHEMBL246378 | 0.83 | PARP10 (0.63) | RYR2METAP1ACHEALDH1A1MAPKAPK2 | |
| SCHEMBL29438649 | 0.83 | PARP10 (0.63) | RYR2METAP1ACHEALDH1A1MAPKAPK2 | |
| SCHEMBL7944009 | 0.82 | METAP1 (0.50) | PDE3BPDE3ARYR2METAP1ACHE | |
| SCHEMBL15553470 | 0.82 | NTRK2 (0.51) | NTRK2CLK4DYRK1BTYRO3KDR | |
| SCHEMBL20992951 | 0.81 | CLK4 (0.47) | NTRK2CLK4DYRK1BTYRO3KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119490507-A | Novel kinase inhibitor | 首药控股(北京)股份有限公司 | 2025-02-21 | — | — | CN | disclosed |
| CN-118580225-A | PRMT5-MTA synergistic inhibitor and application thereof | 甘李药业股份有限公司 | 2024-09-03 | — | — | CN | disclosed |