SCHEMBL31069742

SCHEMBL31069742

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nearest known ligand 0.41

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MME P08473 6/20 0.41
ACE P12821 3/20 0.41
CPA1 P15085 1/20 0.41
ACE2 Q9BYF1 1/20 0.41
LTA4H P09960 4/20 0.34
RAB9A P51151 1/20 0.33
LMNA P02545 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
SDCBP O00560 1/20 0.32
SDC2 P34741 1/20 0.32
ANPEP P15144 1/20 0.32
ECE1 P42892 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27693383 1.00 MME (0.41) MMEACECPA1ACE2LTA4H
SCHEMBL28397469 0.83
SCHEMBL2858866 0.79 TP53 (0.35)
SCHEMBL7836353 0.79 TP53 (0.35)
SCHEMBL2858868 0.79 TP53 (0.35)
SCHEMBL27675088 0.78 ALDH1A1 (0.51) MMELMNA
Water SCHEMBL27383418 0.77 TP53 (0.33)
SCHEMBL27693374 0.75 ACE (0.43) MMEACECPA1ACE2LTA4H
SCHEMBL30715236 0.75 ALDH1A1 (0.39) MMEACECPA1ACE2LMNA
SCHEMBL8591641 0.74 CA12 (0.43) SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4648800-A1 LINKERS, DRUG LINKERS AND CONJUGATES THEREOF AND METHODS OF USING THE SAME Genmab A/S (DK) 2025-11-19 EP disclosed
WO-2024149345-A1 LINKERS, DRUG LINKERS AND CONJUGATES THEREOF AND METHODS OF USING THE SAME PROFOUNDBIO US CO. (US) 2024-07-18 WO disclosed