Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.49 |
| ▸ | STING1 | Q86WV6 | 5/20 | 0.46 |
| ▸ | NAMPT | P43490 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.44 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.44 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.44 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.42 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | TRAP1 | Q12931 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.42 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25405328 | 0.91 | TRPV1 (0.58) | TRPV1STING1KDM4ETAAR1GABRA1 | |
| SCHEMBL25406151 | 0.91 | TRPV1 (0.55) | TRPV1STING1KDM4ETAAR1GABRA1 | |
| SCHEMBL30593236 | 0.91 | TRPV1 (0.58) | TRPV1STING1KDM4ETAAR1GABRA1 | |
| SCHEMBL31070648 | 0.87 | GABRA1 (0.57) | STING1NAMPTKDM4ETAAR1GABRA1 | |
| SCHEMBL31070632 | 0.81 | STING1 (0.53) | TRPV1STING1NAMPTKDM4ETAAR1 | |
| SCHEMBL25407518 | 0.80 | TAAR1 (0.65) | KDM4ETAAR1GABRA1GABRG2GABRB3 | |
| SCHEMBL30593250 | 0.80 | TAAR1 (0.65) | KDM4ETAAR1GABRA1GABRG2GABRB3 | |
| SCHEMBL25405602 | 0.78 | KDM4E (0.49) | TRPV1KDM4ETAAR1GABRA1GABRG2 | |
| SCHEMBL30593244 | 0.78 | KDM4E (0.49) | TRPV1KDM4ETAAR1GABRA1GABRG2 | |
| SCHEMBL25403491 | 0.78 | TAAR1 (0.51) | TRPV1KDM4ETAAR1GABRA1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118515600-A | Isoindoline compound and medical application thereof | 中国科学院上海药物研究所 | 2024-08-20 | — | — | CN | disclosed |