Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 3/20 | 0.36 |
| ▸ | EED | O75530 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | DRD4 | P21917 | 2/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | DRD5 | P21918 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31070671 | 0.72 | SLC6A2 (0.53) | SLC6A2SLC6A4SLC6A3DRD1DRD2 | |
| SCHEMBL7393943 | 0.69 | SLC6A2 (0.47) | SLC6A2SLC6A4SLC6A3DRD1EED | |
| SCHEMBL28510391 | 0.69 | CHRM5 (0.49) | SLC6A2SLC6A4SLC6A3CHRNB2CHRNA4 | |
| SCHEMBL7705422 | 0.69 | SMN1; SMN2 (0.44) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL23442881 | 0.68 | HTR2C (0.47) | SLC6A2SLC6A4SLC6A3EED | |
| SCHEMBL27741885 | 0.68 | DRD1 (0.38) | CHRNB2CHRNA4DRD1DRD2DRD4 | |
| SCHEMBL31444391 | 0.67 | CHRNB2 (0.44) | SLC6A3CHRNB2CHRNA4 | |
| SCHEMBL4301574 | 0.67 | SLC6A2 (1.00) | SLC6A2SLC6A4SLC6A3DRD1 | |
| SCHEMBL31444334 | 0.67 | PRCP (0.42) | CHRNB2CHRNA4 | |
| Methylamine SCHEMBL27463238 | 0.67 | SLC6A2 (0.48) | SLC6A2SLC6A4SLC6A3DRD1EED |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118515600-A | Isoindoline compound and medical application thereof | 中国科学院上海药物研究所 | 2024-08-20 | — | — | CN | disclosed |