Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19243792 | 0.89 | SLC22A12 (0.50) | RPS6KA3KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL17541456 | 0.87 | CYP11B2 (0.62) | PRKCQCYP11B1CYP11B2CYP1A2CYP3A4 | |
| SCHEMBL3990856 | 0.81 | LRRK2 (0.54) | RPS6KA3KDM4EPRKCQCYP11B1CYP11B2 | |
| SCHEMBL17116602 | 0.80 | CYP1A2 (0.42) | RPS6KA3KDM4ECYP11B1CYP11B2CYP1A2 | |
| SCHEMBL28185544 | 0.78 | CYP11B1 (0.54) | KDM4EMEN1KMT2AALDH1A1PRKCQ | |
| SCHEMBL17116727 | 0.78 | HTT (0.42) | RPS6KA3CYP11B1CYP11B2CYP1A2CYP3A4 | |
| SCHEMBL6626450 | 0.78 | RPS6KA3 (0.47) | RPS6KA3KDM4EALDH1A1CYP11B1CYP11B2 | |
| SCHEMBL15997944 | 0.78 | SLC2A1 (0.50) | KDM4EALDH1A1CYP11B1CYP11B2SMN1; SMN2 | |
| SCHEMBL1146097 | 0.78 | CYP1A2 (0.57) | RPS6KA3KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL17120702 | 0.77 | MAPT (0.50) | MEN1KMT2AALDH1A1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12071407-B1 | 6-(4-hydroxyphenyl)-2-(2-ethoxyethoxy)-4-(4-methoxyphenyl)nicotinonitrile as an antimicrobial compound | King Faisal University (SA) | 2024-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12071407-B1 | 6-(4-hydroxyphenyl)-2-(2-ethoxyethoxy)-4-(4-methoxyphenyl)nicotinonitrile as an antimicrobial compound | NAPRT, PNN, NAMPT | RPS6KA3 1684/4885KDM4E 1745/4885MEN1 1953/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.