Known targets — ChEMBL curated mechanism
CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8
The experimentally established mechanism targets of Phloroglucinol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.89 |
| ▸ | LCK | P06239 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 6/20 | 0.50 |
| ▸ | CA9 | Q16790 | 6/20 | 0.50 |
| ▸ | CA2 | P00918 | 5/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | CA5A | P35218 | 5/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | CA5B | Q9Y2D0 | 4/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 5/20 | 0.47 |
| ▸ | CA7 | P43166 | 3/20 | 0.47 |
| ▸ | ABL1 | P00519 | 2/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.47 |
| ▸ | BCR | P11274 | 2/20 | 0.47 |
| ▸ | NQO1 | P15559 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phloroglucinol SCHEMBL5495237 | 1.00 | BACE1 (0.89) | BACE1LCKCA12CA9CA2 | |
| Phloroglucinol SCHEMBL1913949 | 1.00 | BACE1 (0.89) | BACE1LCKCA12CA9CA2 | |
| Phloroglucinol SCHEMBL2889628 | 0.94 | BACE1 (1.00) | BACE1LCKCA12CA9CA2 | |
| Phloroglucinol SCHEMBL26311 | 0.94 | — | — | |
| Phloroglucinol SCHEMBL30542958 | 0.94 | — | — | |
| Phloroglucinol SCHEMBL23346245 | 0.89 | BACE1 (0.89) | BACE1LCKCA12CA9CA2 | |
| Phloroglucinol SCHEMBL31122758 | 0.89 | BACE1 (0.89) | BACE1LCKCA12CA9CA2 | |
| Phloroglucinol SCHEMBL10916023 | 0.89 | BACE1 (0.89) | BACE1LCKCA12CA9CA2 | |
| Phloroglucinol SCHEMBL502610 | 0.89 | BACE1 (0.89) | BACE1LCKCA12CA9CA2 | |
| Phloroglucinol SCHEMBL28934909 | 0.89 | BACE1 (0.89) | BACE1LCKCA12CA9CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 482 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4678020-A1 | AN AEROSOL GENERATING MATERIAL | Nicoventures Trading Limited (GB) | 2026-01-14 | — | — | EP | claimed |
| EP-4678014-A1 | AN AEROSOL GENERATING MATERIAL | Nicoventures Trading Limited (GB) | 2026-01-14 | — | — | EP | claimed |
| EP-4678018-A1 | AN AEROSOL GENERATING MATERIAL | Nicoventures Trading Limited (GB) | 2026-01-14 | — | — | EP | claimed |
| EP-4678019-A1 | AN AEROSOL GENERATING MATERIAL | Nicoventures Trading Limited (GB) | 2026-01-14 | — | — | EP | claimed |
| CN-118084392-B | Soft porcelain facing brick and preparation method thereof | 佛山市卡拉森建材有限公司 | 2024-08-09 | — | — | CN | claimed |
| CN-116077453-B | Phloroglucinol orally disintegrating tablet and preparation method thereof | 湖南科锐斯医药科技有限公司 | 2024-06-11 | — | — | CN | claimed |
| CN-118084392-A | Soft porcelain facing brick and preparation method thereof | 佛山市卡拉森建材有限公司 | 2024-05-28 | — | — | CN | claimed |
| CN-117942301-A | Preparation method and application of phloroglucinol injection | 山西远扬医药科技有限公司 | 2024-04-30 | — | — | CN | claimed |
| CN-117045594-A | Preparation method for improving quality of phloroglucinol injection sample | 北京阳光诺和药物研究股份有限公司 | 2023-11-14 | — | — | CN | claimed |
| CN-113750058-B | Phloroglucinol freeze-dried orally disintegrating tablet and preparation method thereof | 北京九能天远科技有限公司 | 2023-07-04 | — | — | CN | claimed |
| EP-0875532-B1 | Treated clay product, methods of making and using and products therefrom | HUBER CORP J M (US) | 2001-10-31 | — | — | EP | claimed |
| US-5840795-A | TREATING WITH A FUNCTIONAL SILANE, A METHYLENE DONOR COMPOUND SUCH AS HEXAMETHYLENETETRAMINE AND A MULTIFUNCTIONAL METHYLENE ACCEPTOR SUCH AS RESORCINOL | J. M. HUBER CORPORATION (US) | 1998-11-24 | — | — | US | claimed |
| EP-0875532-A1 | Treated clay product, methods of making and using and products therefrom | J.M. HUBER CORPORATION (US) | 1998-11-04 | — | — | EP | claimed |
| EP-0667245-A1 | Recording sheets containing alcohols and saccharides | XEROX CORPORATION (US) | 1995-08-16 | — | — | EP | claimed |
| EP-0446662-B1 | Enhanced reduction and inhibition of ETU content in alkylenebisdithiocarbamates | PENNWALT FRANCE (FR) | 1995-05-24 | — | — | EP | claimed |
| EP-0460612-B1 | Reduction and inhibition of etu content in alkylenebisdithiocarbamates | ATOCHEM AGRI SA (FR) | 1995-05-10 | — | — | EP | claimed |
| US-5100915-A | REDUCTION AND INHIBITION OF ETU CONTENT IN ALKYLENEBISDITHIOCARBAMATES | PENNWALT FRANCE S.A. (FR) | 1992-03-31 | — | — | US | claimed |
| EP-0460612-A1 | Reduction and inhibition of etu content in alkylenebisdithiocarbamates | ATOCHEM AGRI S.A. (FR) | 1991-12-11 | — | — | EP | claimed |
| EP-0446662-A2 | Enhanced reduction and inhibition of ETU content in alkylenebisdithiocarbamates | PENNWALT FRANCE S.A. (FR) | 1991-09-18 | — | — | EP | claimed |
| US-5021594-A | Mixing with formaldehyde donor and copolymerization agent to react with ethylenethiourea | PENNWALT FRANCE S.A. (FR) | 1991-06-04 | — | — | US | claimed |